Dosage : Tablets
Contains : Aceclofenac 100 + Paracetamol 325 + Rabeprazole 20 mg
Category : Pain Management
Uses : Osteoarthritis, Rheumatoid arthritis and Ankylosing spondylitis
Price :

Aciril-PR is prescribed for fever, pain and arthritis. The medication contains Aceclofenac which belongs to the category of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). It has anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action and better or comparable effects than conventional NSAIDs.  The medication inhibits the action of a substance in the body called as cyclo-oxygenase, which may cause pain and swelling, inflammation and fever.


Additionally, Paracetamol in Aciril-PR is used to treat many conditions like muscle aches, arthritis, backache and fevers. It acts as a pain reliever in mild arthritis. Aciril-PR also contains Rabeprazole which is helpful in the treatment of hyperacidity and acid reflux. It offers relief for symptoms like difficulty in swallowing, persistent cough and heartburn.


Aciril-PR is manufactured by Merril Pharma, a company based in Haridwar, India assuring breakthrough modern healthcare products and services to the healthcare industry. The company manufactures supplies and distributes the finest quality medication used for the treatment of various life threatening diseases and conditions. Merril Pharma is focused on providing world class quality products and excellence in the marketing of a vital range of specialist products that enhance the well-being of patients.

Osteoarthritis, Rheumatoid Arthritis or Ankylosing Spondylitis.


Rheumatoid arthritis is an autoimmune disease which occurs when a person’s immune system mistakenly attacks healthy tissues in the joints. In Osteoarthritis, the protective cartilage gradually wears down as the bones at the joints begin to scrape against one another due to repetitive movements and unnecessary pressure on joints. Rheumatoid arthritis occurs in smaller joints of the body, while Osteoarthritis is seen in bigger joints like hip and knee joints.


Some of the symptoms of Rheumatoid Arthritis are fatigue, fever, loss of appetite, rheumatoid nodules, weight loss and inflammation in other areas such as the eyes and lungs.


Those suffering from Osteoarthritis can develop bone spurs or other bone abnormalities.


Treatment for Rheumatoid and Osteoarthritis includes medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce inflammation, alleviate pain and stiffness in the joints and improve their range of motion. Physiotherapy may also be suggested to keep the joints flexible and help improve a person’s mobility.


Ankylosing spondylitis (AS) is a type of arthritis that affects the spine causing pain, stiffness, and inflammation from the neck to lower back. In AS, the vertebrae in your spine can fuse together making it less flexible and causing a hunched-over posture and difficulty in breathing.


Treatments for AS include nonsteroidal anti-inflammatory drugs (NSAIDs), Corticosteroid shots in your joints, Disease-modifying anti rheumatic drugs (DMARDs), Biologic DMARDs. Surgery may be recommended for a curved spine or neck, damaged knees and hips.


As directed by your Physician


As directed by your Physician

Adverse Reactions/ Side Effects

Nausea, Diarrhea, Constipation, Stomach pain, Flatulence, Loss of appetite, Weakness, Flu-like symptoms.

Warnings and Precautions


Drug Interactions



Mechanism of Action

Aceclofenac + Paracetamol/Acetaminophen + Rabeprazole is a combination of two pain relievers (Aceclofenac + Paracetamol/Acetaminophen + Rabeprazole1, Aceclofenac + Paracetamol/Acetaminophen + Rabeprazole2) and a proton pump inhibitor (Aceclofenac + Paracetamol/Acetaminophen + Rabeprazole3). The pain relievers work by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). However, they may cause damage to the stomach lining. The proton-pump inhibitor is added to reduce acid secretion and prevent this damage.

References › paracetamol

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