ALLEGRA

Dosage : Tablet
Contains : Fexofenadine hydrochloride
Category : Antihistamine
Uses : Seasonal allergies, urticaria, including sneezing, itchy palate, runny nose, tearing, and redness of the eyes .
Price :

Allegra is an antihistamine in the form of tablet. It is also known as second-generation antihistamine that reduces the effects of natural chemical histamine in the body. This natural chemical histamine can lead to allergies with symptoms like sneezing, itching, watery eyes, and runny nose.

 

Allegra does not cause sedation and is approved by the Federal Aviation Administration (FAA) for use by pilots.

 

Allergra is composed of fexofenadine hydrochloride molecule, that blocks the action of histamine at the H1 receptor (signal receptors in neurons), helping to relieve allergic reactions.

 

Fexofenadine helps in relieving symptoms associated with seasonal and year-round allergies including sneezing, itchy palate, runny nose, and itchy, tearing, and redness of the eyes. It is also used to relieve the symptoms associated with an allergic skin reaction (chronic idiopathic urticaria) including hives and itchy skin

 

Allegra is manufactured by Sanofi Limited . Sanofi was incorporated in May 1956 and is one of the world’s leading pharmaceutical companies. It has 79 manufacturing sites in 36 countries

Your doctor may have prescribed Allegra because you could be suffering from Allergic reactions and symptoms.

 

Allegra is an orally available medication that contains the active substance Fexofenadine which blocks the action of the body’s natural chemical histamine which is responsible for many of the symptoms caused by an allergy. It has to be taken as directed by your physician in the right doses.

 

Allergic symptoms are caused by your immune system due to various allergens that may trigger an allergic reaction. Allergies are dependant on your genes and can vary from person to person.

 

Allergic reactions happen when the immune system recognises an allergen and the cells release histamines which causes inflammation in that region. This prompts the immune system to respond to the inflammation and start deep repair.

Dosage

As directed by your physician

Administration

As directed by your physician

Adverse Reactions/ Side Effects

Nervous: Headache, dizziness, drowsiness, fatigue, insomnia, paroniria, psychomotor impairment. CV:Palpitations, tachycardia. GI: Nausea, dyspepsia, diarrhoea. Resp: Upper resp tract infections, sinusitis.Genitourinary Urinary retention. Dermatologic: Rash, pruritus, urticaria. Immunologic: Hypersensitivity reactions, viral infection (e.g. influenza). Others: Back pain, dysmenorrhea.

Warnings and Precautions

Patient w/ active history of CV disease. Childn. Renal and hepatic impairment. Pregnancy and lactation.

Contraindications

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Drug Interactions

Increased plasma concentrations w/ erythromycin and ketoconazole. Reduced absorption w/ antacids containing Al and Mg hydroxide.

Overdosage

Symptoms: Dizziness, drowsiness, dry mouth, fatigue. Management: Symptomatic and supportive treatment.

Storage

Oral: Store between 20-25°C.

Mechanism of Action

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References

https://www.sanofi.com/en/about-us

https://www.drugs.com/search.php?searchterm=Allegra&a=1

https://www.allegra.com/products/

“A review of the efficacy of desloratadine, fexofenadine, and levocetirizine in the treatment of nasal congestion in patients with allergic rhinitis”. Clin   Ther. 31 (5):    921–44. doi:10.1016/j.clinthera.2009.05.017. PMID 19539095.

https://www.mims.com/india/drug/search?q=ALLEGRA

https://www.allegra.com/hcp/

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