AVIL

Dosage : Tablet 25, 50 mg, Syrup 15mg/ml
Contains : Pheniramine maleate
Category : Systemic Antihistamine
Uses : Allergy, urticaria
Price :

Avil is an antihistamine with a little sedative action. It is used to prevent or treat allergic reactions like hay fever or urticaria caused by pollen, dust, or animal hair. Use of this medicine in children under the age of 5 years is not recommended.

 

Avil contains Pheniramine. Pheniramine is an antihistamine combination. It works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. Relieving symptoms of runny nose and sneezing due to colds, upper respiratory infections, and allergies.

 

Avil is a product from Sanofi S.A. Sanofi is a French multinational pharmaceutical company headquartered in Paris, France, Sanofi engages in the research and development, manufacturing and marketing of pharmaceutical drugs principally in the prescription market, but the firm also develops over-the-counter medication. The company covers seven major therapeutic areas: cardiovascular, central nervous system, diabetes, internal medicine, oncology, thrombosis and vaccines (it is the world’s largest producer of the latter through its subsidiary Sanofi Pasteur).

Allergies

 

Allergies occur when your immune system reacts to a foreign substance — such as pollen, bee venom or pet dander — or a food that doesn’t cause a reaction in most people.

 

Your immune system produces substances known as antibodies. When you have allergies, your immune system makes antibodies that identify a particular allergen as harmful, even though it isn’t. When you come into contact with the allergen, your immune system’s reaction can inflame your skin, sinuses, airways or digestive system.

 

The severity of allergies varies from person to person and can range from minor irritation to anaphylaxis, a potentially life-threatening emergency. While most allergies can’t be cured, treatments can help relieve your allergy symptoms.

Dosage

As directed by your Physician

Administration

As directed by your Physician

Adverse Reactions/ Side Effects

Sedation. Hypersensitivity reactions. Lassitude, dizziness, tinnitus, inability to concentrate, incoordination, irritability, insomnia and tremors. Nausea, vomiting, diarrhoea, colic, epigastric pain, anorexia, dryness of mouth and constipation. Urinary retention. Palpitations, headache. Blurred vision, increased intraocular pressure. Muscular weakness. Rarely, blood dyscrasias e.g. agranulocytosis, haemolytic anaemia. Ophthalmic: Temporarily enlarged pupils, eye redness (overuse).

Warnings and Precautions

May impair ability to drive or operate machinery. Has potential for abuse. Narrow angle glaucoma, asthma or severe CV disease. Antiemetic effect may mask signs of other conditions. Pregnancy and lactation. Elderly.

Contraindications

  • Pheniramine and Pregnancy
  • Caution when used during pregnancy
  • Pheniramine and Lactation
  • Caution when used during lactation
  • Pheniramine and Other Contraindications
  • Symptomatic prostatic hypertrophy; neonates and premature infants.

Drug Interactions

May mask ototoxicity produced by aminoglycoside antibiotics.

 

Potentially Fatal: Potentiation of CNS depression by alcohol, sedatives, opioids, barbiturates, hypnotics, narcoleptics. May increase antimuscarinic effect of MAOIs, atropine and TCAs.

Overdosage

Storage

Ophthalmic: Store at 20-25°C (68-77°F). Protect from light.

Oral: Tablet: Store below 30°C (86°F). Protect from light.

Mechanism of Action

References

http://www.drugsupdate.com/generic/view/396

https://en.wikipedia.org/wiki/Sanofi

https://www.mayoclinic.org/diseases-conditions/allergies/symptoms-causes/syc-20351497

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