Suppression of HPA axis, growth suppression especially in children, menstrual irregularity and amenorrhoea, Cushingoid facies, hirsutism, weight gain, impaired carbohydrate tolerance, increased appetite, hyperhidrosis; recurrence of dormant TB, opportunistic infections; osteoporosis, vertebral and long bone fractures, avascular osteonecrosis, tendon rupture, proximal myopathy; Na and water retention, HTN, K loss, hypokalaemic alkalosis; affective disorder (e.g. irritable, euphoric, depressed and labile mood, suicidal thoughts), psychotic reactions ( e.g. mania, delusions, hallucinations and aggravation of schizophrenia), behavioural disturbances.
Also, irritability, anxiety, sleep disturbances and cognitive dysfunction (e.g. confusion, amnesia), epilepsy aggravation; increased intraocular pressure, glaucoma, papilloedema, posterior subcapsular cataracts, corneal or scleral thinning, exacerbation of ophth viral or fungal disease; abdominal distension, oesophageal ulceration, nausea, dyspepsia, peptic ulceration w/ perforation and haemorrhage, acute pancreatitis, candidiasis; impaired healing, skin atrophy, bruising, telangiectasia, striae, acne, Stevens-Johnson syndrome; thrombo-embolism, malaise, hiccups.