BRILINTA

Dosage : Tablet
Contains : Ticagrelor
Category : Anticoagulants, Antiplatelets & Fibrinolytics (Thrombolytics)
Uses : Acute coronary syndrome
Price :

Brilinta is an oral antiplatelet drug that is used with low dose aspirin to decrease the risk of myocardial infarction (heart attack) and stroke in patients with acute coronary syndrome.

 

A heart attack happens when one or more of the arteries that supply blood to heart gets blocked. Due to this heart does not get enough oxygen that it needs to function. With the right medications and lifestyle changes, one can reduce the risk of another heart attack or stroke. Platelet (blood cells) P2Y12 receptors play a key role in platelet activation and thrombus (clot) formation. Platelets can gather and stick together to form another clot in artery causing another heart attack. After the plaque ruptures, Brilinta helps stop platelets from reacting and forming a new and dangerous clot that could cause another heart attack.

 

Brilinta is indicated to reduce the rate of cardiovascular death, myocardial infarction, and stroke in patients with acute coronary syndrome (ACS) or a history of myocardial infarction. Brilinta also reduces the rate of stent thrombosis in patients who have undergone treatment of ACS.

 

Brilinta is a brand from AstraZeneca a global, science-led biopharmaceutical company. The company’s innovative medicines are used by millions of patients worldwide. AstraZeneca is considered as one of the 100 Most Sustainable Corporations in the world.

Acute coronary syndrome is a term used to describe a range of conditions associated with sudden, reduced blood flow to the heart.

 

One such condition is a heart attack (myocardial infarction) – when cell death results in damaged or destroyed heart tissue. Even when acute coronary syndrome causes no cell death, the reduced blood flow changes how your heart works and is a sign of a high risk of heart attack.

 

Acute coronary syndrome often causes severe chest pain or discomfort. It is a medical emergency that requires prompt diagnosis and care. The goals of treatment include improving blood flow, treating complications and preventing future problems.

Dosage

As directed by your Physician

Administration

As directed by your Physician

Adverse Reactions/ Side Effects

The following is a list of possible side-effects that may occur from all constituting ingredients of Brilinta. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious.

 

Consult your doctor if you observe any of the following side-effects, especially if they do not go away.

  • Diarrhea or indigestion
  • Feeling dizzy
  • Abdominal pain
  • Tingling feeling
  • Bruising
  • Breathing difficulties
  • Itching
  • Confusion
  • Nose bleeding
  • Constipation

Warnings and Precautions

Before using Brilinta Tablet, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counselling points are listed below.

 

Consult with doctor in case of abnormally low heart rate, asthma, lung problems, breathing difficulties or increased levels of uric acid

Contraindications

Hypersensitivity to Brilinta is a contraindication. In addition, Brilinta should not be used if you have the following conditions:

  • Allergic
  • Bleeding in stomach or gut from an ulcer
  • Moderate to severe liver disease
  • Stroke caused by bleeding in the brain

Drug Interactions

If you use other drugs or over the counter products at the same time, the effects of Brilinta Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions.

 

Brilinta may interact with the following drugs and products:

  • Cisapride
  • Digoxin
  • Diltiazem
  • Ketoconazole
  • Rifampin
  • Simvastatin

Overdosage

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Storage

Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.

 

Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Brilinta Tablets.

Mechanism of Action

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References

https://www.tabletwise.com/brilinta-tablet

https://www.drugs.com/dosage/brilinta-tablets.html

https://www.mayoclinic.org/diseases-conditions/acute-coronary-syndrome/symptoms-causes/syc-20352136

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