Cadomer ointment when applied on wound absorbs fluid, removes exudates, pus and debris from the wound surface. One gram of cadexomer iodine ointment can absorb a minimum of 2.5 ml of fluid. Iodine is physically immobilized within the matrix of the dry cadexomer iodine and is slowly released in an active form during uptake of wound fluid. This mechanism of release provides antibacterial activity both at the wound surface and within the formed gel. There is no evidence of the development of bacterial resistance to iodine. The formed layer can easily be removed without damaging the fragile new cells underneath.
Cadomer ointment reduces the bacterial count, facilitates de-sloughing, absorbs exudates and maintains a moist environment to promote healing of chronic skin ulcers.
Cadomer is indicated for the treatment of chronic exuding wounds such as leg ulcers, pressure ulcers and diabetic ulcers, infected traumatic and surgical wounds.
Diabetic ulcers are most commonly caused by:
high blood sugar (hyperglycemia)
irritated or wounded feet
Poor blood circulation is a form of vascular disease in which blood doesn’t flow to your feet efficiently. Poor circulation can also make it more difficult for ulcers to heal.
High glucose levels can slow down the healing process of an infected foot ulcer, so blood sugar management is critical. People with type 2 diabetes often have a harder time fighting off infections from ulcers.
Nerve damage is a long-term effect and can even lead to a loss of feeling in your feet. Damaged nerves can feel tingly and painful at first. Nerve damage reduces your sensitivity to foot pain and results in painless wounds that can cause ulcers.
As directed by your physician
As directed by your physician
Adverse Reactions/ Side Effects
Patients treated with cadexomer iodine ointment may experience a transient smarting or pain within the first hour after application. Minor reddening or swelling around the wound may occur without necessarily being an allergic reaction. Contact allergy and local edema have been reported.
Warnings and Precautions
Iodine may be absorbed systematically, when large wounds are treated. Patients with severely impaired renal function or a past history of any thyroid disorder are more susceptible to alterations in thyroid metabolism with chronic Cadomer ointment therapy. In endemic goitre there have been isolated reports of hyperthyroidism associated with exogenous iodine. It has been observed occasionally that an adherent crust can form when Cadomer ointment is not changed at required frequency. Cadomer is not effective in treating dry wounds
Patients with known or suspected iodine sensitivity
Patients with history of Graves’ disease or Non-toxic nodular goitre
Children under 12 years of age
Pregnant or lactating women
There is a potential risk of interaction with lithium, resulting in an increased possibility of hypothyroidism. Cadomer ointment should not be used concomitantly with taurolidine (since there is a risk of metabolic acidosis) or with mercurial antiseptics, e.g. mercurochrome and thiomersal. Since iodine may be absorbed systemically, the result of tests of thyroid function can be influenced.
There have been no reported over dosages. In case of excessive topical use of Cadomer the treatment should be stopped, the area is washed and symptomatic treatment is initiated.
Store below 30°C
Do not expose to sunlight
Keep out of reach of children
Mechanism of Action
Data provided by J. B. CHEMICALS AND PHARMACEUTICALS LTD.
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