CANDID

Dosage : Gel, Cream, Lotion, Powder, Ear drops
Contains : Clotrimazole
Category : Antifungal
Uses : Ringworm infections, Fungal Ear infections
Price :

Candid contains Clotrimazole. Clotrimazole is an antifungal medication commonly used in the treatment of fungal infections of both humans and animals such as vaginal yeast infections, oral thrush, and ringworm. It is also used to treat athlete’s foot and jock itch. Clotrimazole belongs to the class of imidazole and triazole derivatives.

 

Candid is a product from Glenmark. Glenmark is a leading, research based global pharmaceutical company established in 1977 with its headquarters based in Mumbai.

 

Glenmark has focused on building a global Innovative/Specialty, Generics and OTC business in the therapy areas of Dermatology, Respiratory and Oncology. It also has strong regional/country-specific presence in other therapeutic areas like diabetes, cardiovascular and oral contraceptives.

Ringworm Infections

 

Ringworm also known as dermatophytosis, dermatophyte infection, or tinea, is a fungal infection of the skin.

 

Ringworm infection can affect both humans and animals. The infection initially appears as red patches on affected areas of the skin and later may spread to other parts of the body. It may affect the scalp, feet, nails, groin, beard, or other areas.

 

Different types of fungi cause ringworm. Doctors call ringworm different names depending on where it affects the body:

 

Ringworm of the scalp (tinea capitis) often starts as isolated scaling in the scalp that develops into itchy, scaly bald patches. It’s most common among children.

 

Ringworm of the body (tinea corporis) often appears as patches with the characteristic round ring shape.

 

Jock itch (tinea cruris) refers to ringworm infection of the skin around the groin, inner thighs, and buttocks. It’s most common in men and adolescent boys.

 

Athlete’s foot (tinea pedis) is the common name for ringworm infection of the foot. It’s frequently seen in people who go barefoot in public places where the infection can spread, such as locker rooms, showers, and swimming pools.

 

Otomycosis

 

Otomycosis is a fungal infection that affects one, or occasionally both, of the ears. It mostly affects people who live in warm or tropical areas. It also often affects people who swim frequently, live with diabetes, or have other chronic medical and skin conditions.

Dosage

As directed by your Physician

Administration

As directed by your physician

Adverse Reactions/ Side Effects

Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning, and general irritation of the skin, and cramps. As with all topical agents, skin sensitization may result.

Warnings and Precautions

Ear drops: Perforated eardrum.

 

Use in Pregnancy: There are limited data regarding the use of clotrimazole in pregnant women. Although the topical application of clotrimazole may result in very low serum and tissue levels, the use of clotrimazole topical cream by pregnant women is not recommended unless it is advised by the prescribing physician.

 

Use in Breastfeeding: Clotrimazole should not be administered during breastfeeding. Although the topical application of clotrimazole has resulted in very low serum and tissue levels, the use of clotrimazole topical cream by lactating women is not recommended unless it recommended by the prescribing physician.

Contraindications

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Drug Interactions

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Overdosage

This drug poses no risk of acute intoxication, as it is unlikely to occur following a single vaginal or dermal application of an overdose (application over a large area under conditions favorable to absorption) or accidental oral ingestion. There is no specific antidote.

Storage

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Mechanism of Action

Clotrimazole acts primarily by damaging the permeability barrier in the cell membrane of fungi. Clotrimazole causes inhibition of ergosterol biosynthesis, an essential constituent of fungal cell membranes. If ergosterol synthesis is either completely or partially inhibited, the cell is no longer able to construct an intact and functional cell membrane. Because ergosterol directly promotes the growth of fungal cells in a hormone‐like fashion, rapid onset of the above events leads to dose-dependent inhibition of fungal growth.

References

https://www.healthline.com/health/ringworm#causes

http://www.drugsupdate.com/brand/generic/Clotrimazole/5233

https://www.mims.com/malaysia/drug/info/candid%20ear%20drops-lotion-cream-dusting%20powder

https://www.drugbank.ca/drugs/DB00257

https://www.healthline.com/health/otomycosis

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