CEFAKIND

Dosage : Tablet
Contains : Cefuroxime
Category : Cephalosporin (antibiotic)
Uses : Upper respiratory tract infections, Lower respiratory tract infections, Genito-urinary tract infections, Skin and soft tissue infections
Price :

Cefakind contains cefuroxime molecule, is an oral third generation cephalosporin (antibiotic). It is active against most Gram positive and Gram negative organisms such as Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. Cefpodoxime is commonly used to treat acute otitis media, pharyngitis, and sinusitis

 

Cefuroxime inhibits the final protein synthesis in bacterial cell wall, thus inhibiting biosynthesis (growth) thereby leading to the bacterial cell damage and death. Cefakind is a broad-spectrum antibiotic used to treat a variety of conditions such as Lyme disease; infections of the ears, lungs, urinary tract, etc. caused by bacteria. It is available in 125mg, 250mg and 500mg strength and is advised to be taken with food.

 

Cefakind is product from Mankind pharma. Mankind Pharma is a pharmaceutical company in India based at New Delhi. The company has products in therapeutic areas ranging from antibiotics, to gastrointestinal, cardiovascular, dermal, and erectile dysfunction medications. They are covering Industrial sectors in Pharmaceuticals, Medical Research & Laboratories domain. Mankind Pharma Ltd is a public company.

You may have been prescribed Cefakind because you could be suffering from Bacterial Infections.

 

Cefakind is an orally available antibiotic medication that contains the active substance Cefuroxime which interferes with the growth mechanism of bacteria. It is a broad spectrum antibiotic as it can be used to treat a wide variety of bacterial infections. It works by stopping the growth of the bacteria involved.

 

Bacterial Infections are caused by infectious bacteria which reproduce quickly in the body and may even give out toxins which can damage tissues and make you very ill.

 

Bacterial Infections differ from other infections due to the microbes that cause them. Even though less than one percent of bacteria can humans sick, bacterial infections can range from minor illnesses such as strep throat and ear infections to more life-threatening conditions like meningitis and encephalitis.

 

Patients infected by bacteria have to be treated with antibiotics. Cefuroxime can be used to treat a wide range of bacterial infections that may include:

  • Pharyngitis
  • Tonsillitis
  • Acute Bacterial Otitis Media
  • Sinusitis
  • Bronchitis
  • Skin and Structure Infection
  • Cystitis
  • Pyelonephritis
  • Lyme disease
  • Gonococcal Infection

 

Cefakind has been known to work well among patients with mild to serious bacterial infection across a broad spectrum.

Dosage

As directed by your Physician

Administration

As directed by your Physician

Adverse Reactions/ Side Effects

Rash, fever, pruritus, erythema, urticaria, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, serum sickness-like reactions, angioedema; mild to moderate hearing loss (children); nausea, vomiting, gagging, epigastric burning, GI bleeding and infection, abdominal pain, flatulence, ptyalism, indigestion, mouth ulcers, swollen tongue, anorexia, thirst, dyspepsia, stomach cramps, diarrhoea; decreased Hb and haematocrit, thrombocytosis, lymphocytosis, haemolytic anaemia, increased prothrombin time; transient increase in serum AST (SGOT), ALT (SGPT), alkaline phosphatase, LDH and bilirubin levels; transient increase in BUN and/or serum creatinine concentration, decreased CrCl, bilateral renal cortical necrosis; UTI, kidney pain, urethral pain or bleeding, dysuria, vaginitis, vaginal candidiasis, vulvovaginal pruritus, vaginal discharge or irritation; Jarisch-Herxheimer reaction; neck muscle spasm, muscle cramps or stiffness, chest pain or tightness, shortness of breath, tachycardia, chills, lockjaw-type reaction, viral illness, upper respiratory infection, sinusitis, cough, joint swelling, arthralgia; pain at injection site, thrombophlebitis (IV). Rarely, transient eosinophilia and neutropenia, pancytopenia, leucopenia, thrombocytopenia; headache, somnolence or sleepiness, dizziness, hyperactivity, irritable behaviour, myoclonic jerks, seizures, generalised hyperexcitability; jaundice; acute renal failure, interstitial nephritis.

 

Potentially Fatal: Anaphylaxis, pseudomembranous colitis.

Warnings and Precautions

History of hypersensitivity to penicillin, and GI disease (particularly colitis). Renal impairment. Pregnancy and lactation. Monitoring Parameters Monitor renal, hepatic and haematologic function periodically. Monitor prothrombin time in patients at risk of prolongation. Observe for signs and symptoms of anaphylaxis during 1st dose.

Contraindications

Hypersensitivity to cefuroxime or to other cephalosporins.

Drug Interactions

May enhance the nephrotoxic effect of strong-acting diuretics (e.g. furosemide) and aminoglycosides. May enhance the effect of oral anticoagulants. May reduce the efficacy of OCs. Probenecid prolongs the excretion of cefuroxime and elevated peak serum level.

Overdosage

Symptoms: Encephalopathy, convulsions and coma. Management: Haemodialysis or peritoneal dialysis may reduce serum levels.

Storage

Oral: Tab: Store between 15-30°C. Powder for oral suspension: Store between 2-30°C. After reconstitution: Store between 2-8°C.

Mechanism of Action

–

References

https://www.ncbi.nlm.nih.gov/pubmed/8799689

https://www.medicines.org.uk/emc/medicine/30850#

https://www.medicines.org.uk/emc/medicine/30850#

https://en.wikipedia.org/wiki/Mankind_Pharma

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