Cetzine is an effective prescription medication to treat allergic symptoms of Rhinitis like sneezing, runny nose and watery eyes. Cetzine is composed of Cetirizine which offers high potency for relieving nasal blockage, rhinorrhea, itching and swelling. Cetirizine provides high quality protection with a dual action for treatment against both skin and nasal allergies.
Cetirizine is an anti-histamine which has been found to be very efficacious, offering rapid action. Cetirizine works by blocking a certain natural substance known as histamine which is made by the body during an allergic reaction. The effect of Cetirizine occurs within 20 minutes in 50% patients consuming it and within an hour in 95% patients. Further, the effects of a single dose last for at least 24 hours. Besides relieving symptoms associated with seasonal allergies, it is also prescribed in Urticaria to treat symptoms like itchy skin, swelling and raised welts on the skin.
Cetzine is manufactured by Dr. Reddy’s Laboratories (DRL) an Indian multinational pharmaceutical company based in Hyderabad, Telangana, India. The company has a state-of-the-art R&D Centre housing 70 laboratories with over 800 research scientists working on various projects. It works closely with other centres across the UK and the Netherlands, offering wide-ranging access to affordable and innovative medicines – from synthetic organic chemistry to formulations development; from intellectual property management to regulatory science; from polymorphism to bio-pharmaceutics.
Your may have been prescribed Cetzine as you may be diagnosed with Seasonal Allergic rhinitis, Perennial Allergic Rhinitis or Urticaria.
Allergic rhinitis or hay fever causes cold-like signs and symptoms such as a runny nose, itchy eyes, congestion, sneezing, allergic conjunctivitis and sinus pressure. It is caused by an allergic response to outdoor or indoor allergens such as pollen, dust mites or tiny flecks of skin and saliva shed by cats, dogs and other animals with fur or even from feathers.
Medications for hay fever include nasal corticosteroids, antihistamines, decongestants, allergy shots (immunotherapy) and rinsing of sinuses.
Perennial allergic rhinitis is a chronic allergic condition that causes nasal congestion and a runny nose. The most common cause of perennial allergic rhinitis are dust mites and pet dander from cats and dogs. It can also be caused by any allergy that is present year round.
To treat perennial allergic rhinitis, using a dehumidifier, if you are allergic to dust mites can be helpful. Other actions suggested are getting rid of pets or limiting their access to bedrooms, regular and deep cleaning, dry cleaning or replacing carpets at home. Patients are recommended medications including antihistamines for controlling allergy symptoms and if required, immunotherapy.
Urticaria or hives is an outbreak of swollen, itchy, pale red bumps or wheals on the skin due to the body’s reaction to certain allergens. An allergic reaction triggers the body to release a protein called histamine. The histamine causes inflammation and fluid begins to accumulate under the skin causing wheals. When new outbreaks happen almost every day for 6 weeks or more, it’s called chronic idiopathic urticaria (CIU).
Causes of Urticaria include stress or underlying autoimmune disorders like thyroid dysfunction, food allergies and viruses which can trigger hives.
Treatment for acute urticaria includes non-sedating antihistamines taken regularly for several weeks. Antibiotics may also be needed for chronic urticaria. Some other actions to prevent Urticaria include wearing loose, light clothing, avoiding scratching and using harsh soaps, avoiding known triggers and applying sunscreen when outdoors.
Respiratory, thoracic and mediastinal disorders: Pharyngitis, rhinitis, epistaxis, bronchospasm. Skin and subcutaneous tissue disorders: Pruritus, rash, urticaria.
Warnings and Precautions
Patients with increased risk of urinary retention (e.g. spinal cord lesion, prostatic hyperplasia), epileptic and patients at risk of convulsions. Hepatic and mild to moderate renal impairment. Children. Pregnancy and lactation. Patient Counselling This drug may cause CNS depression (e.g. somnolence), if affected, do not drive or operate machinery. Monitoring Parameters Monitor relief of symptoms, sedation and anticholinergic effects.
Severe renal impairment.
Additive CNS depression when administered concomitantly with other CNS depressants (e.g. sedatives, tranquillisers).
Symptoms: Confusion, diarrhoea, dizziness, fatigue, headache, malaise, mydriasis, pruritus, restlessness, sedation, somnolence, stupor, tachycardia, tremor, urinary retention. Management: Symptomatic and supportive treatment. Gastric lavage may be performed following early ingestion.
Store between 20-25°C
Mechanism of Action
Cetirizine, a piperazine derivative and metabolite of hydroxyzine, is an antihistamine which competitively and selectively inhibits H1 receptors in the gastrointestinal tract, blood vessels, and respiratory tract.