Digene is India’s No. 1 prescribed brand amongst antacids. Digene formulation is scientifically proven to cure acidity quickly, effectively with long lasting relief.
Digene’s High ANC (Acid Neutralizing Capacity) effectively neutralizes the excess acids in stomach and gives relief from acidity. The anti-flatulent property helps in reducing bloating, discomfort or pain caused by excessive gas.
Digene Gel contains aluminium hydroxide, magnesium hydroxide, simethicone, sodium carboxymethylcellulose. Aluminium hydroxide neutralises the acid in stomach resulting in increased gastric pH and inhibition of pepsin activity.
Digene is available in Gel, Tablet, Fizz and Pearl form.
Digene is used in following conditions:
Symptomatic relief of peptic ulcer
Other dyspeptic conditions associated with hyperacidity
Digene is a product of Abbott, a multinational pharmaceutical company that
functions in various therapy areas. The company has a diverse range of science-based nutritional products, diagnostic tools, branded generic pharmaceuticals, and diabetes and vascular devices. The company operates in more than 150 countries globally.
Gastritis is a general term for a group of conditions with one thing in common: inflammation of the lining of the stomach. The inflammation of gastritis is most often the result of infection with the same bacterium that causes most stomach ulcers. Regular use of certain pain relievers and drinking too much alcohol also can contribute to gastritis.
Gastritis may occur suddenly (acute gastritis), or appear slowly over time (chronic gastritis). In some cases, gastritis can lead to ulcers and an increased risk of stomach cancer. For most people, however, gastritis isn’t serious and improves quickly with treatment.
The signs and symptoms of gastritis include:
Gnawing or burning ache or pain (indigestion) in your upper abdomen that may become either worse or better with eating
A feeling of fullness in your upper abdomen after eating
Patient w/ restricted phosphate intake, low Na diet, uraemia, heart failure, oedema, recent GI haemorrhage. Hepatic (e.g. cirrhosis) and renal (e.g. chronic renal failure) impairment. Pregnancy. Patient Counselling Avoid application over deep and puncture wounds, infected areas, or lacerations. Monitoring Parameters Monitor serum Ca and phosphate levels regularly when patient is on chronic therapy.
Hypophosphataemia, acute porphyria.
May interfere w/ the absorption of some drugs including tetracyclines, penicillin, sulfonamides, Fe, digoxin, indometacin, naproxen, phenylbutazone, quinidine and vit. Absorption is enhanced by citrates or ascorbic acid.
Symptoms: Phosphate depletion, (manifested in muscle weakness, anorexia, malaise) which may lead to osteomalacia, osteoporosis, or urinary calculi. Management: Employ gastric lavage, and if necessary, followed by a mild aperient.
Oral: Store below 30°C. Topical/Cutaneous: Store below 30°C.
Mechanism of Action
Aluminium hydroxide neutralises HCl in the stomach resulting in increased gastric pH and inhibition of pepsin activity. Additionally, it reduces absorption of phosphate by binding and forming insoluble complexes in the GI tract.