Syrup Grilinctus is a combination of dextromethorphan hydrobromide, chlorpheniramine maleate, guaifenesin, and ammonium chloride.Dextromethorphan exhibits an antitussive activity meaning it works on the cough center in the brain, thereby suppressing the cough reflex. Chlorpheniramine maleate is one of the most widely used of the classical antihistamines. It is used in allergic reactions, hay fever, rhinitis, urticaria, and asthma.
Guaifenesin is an expectorant with some muscle relaxing action. It reduces the viscosity of mucus by reducing its adhesiveness and surface tension. It also increases hydration of mucus. Hence, it thins mucus and lubricates the airway, facilitating an easy removal of mucus by coughing. Ammonium chloride exerts an expectorant effect by irritating the mucous membranes.
These drugs in combination helps alleviate cough of various etiology.
Grilinctus is a brand of Franco-Indian Pharmaceuticals Pvt. Ltd. (FIPPL). Founded in 1949, FIPPL is one of the most reputed pharmaceutical companies in the country.
The company also has a vibrant global presence and exports its formulations to Asia and Africa, besides reaching out to the markets in UK, France and USA.