Mox-CV is a combination medicine containing the semisynthetic antibiotic Amoxycillin and the βlactamase inhibitor, Potassium clavulanate (βlactamase is a type of enzyme produced by bacteria that resists Amoxycillin action). Amoxycillin has a bactericidal effect. However, it is susceptible to hydrolysis by β-lactamases. Addition of clavulanic acid extends the antimicrobial spectrum and activity of amoxycillin. β-lactamase resistance is an increasing problem that results in treatment failure in many common infections. Augmentin first overcomes the β-lactamase resistance, then deals with the bacteria.
Mox-CV is indicated in various bacterial infections like, Skin and Skin Structure Infections, Urinary Tract Infections, Upper Respiratory Tract Infections.
Lower Respiratory Tract Infections. It is available in an injectable, tablet, dry syrup and drops form.
Mox-CV is a brand from Sun Pharma. Sun Pharmaceutical Industries Limited is an Indian multinational pharmaceutical company headquartered in Mumbai, Maharashtra that manufactures and sells pharmaceutical formulations and active pharmaceutical ingredients (APIs) primarily in India and the United States.
The company offers formulations in various therapeutic areas, such as cardiology, psychiatry, neurology, gastroenterology and diabetology. It also provides APIs such as warfarin, carbamazepine, etodolac, and clorazepate, as well as anti-cancers, steroids, peptides, sex hormones, and controlled substances.
Your doctor may have prescribed Mox CV because you could be suffering from Bacterial Infections.
Mox CV is an orally available combination antibiotic drug. The medicine contains two combinations. Amoxicillin is a penicillin-type antibiotic which works by preventing bacteria from growing and killing them. Clavulanic Acid, when combined with penicillin-group antibiotics, can overcome antibiotic resistance in bacteria, which otherwise inactivates most penicillins.
Bacterial Infections are caused by infectious bacteria which reproduce quickly in the body and may even give out toxins which can damage tissues and make you very ill.
Bacterial Infections differ from other infections due to the microbes that cause them. Even though less than one percent of bacteria can humans sick, bacterial infections can range from minor illnesses such as strep throat and ear infections to more life-threatening conditions like meningitis and encephalitis.
Patients infected by bacteria have to be treated with antibiotics. Mox CV can be used to treat bacterial infections that may include:
Middle ear infection
Urinary tract infection
Mox CV has been proven to work well among patients with mild to serious bacterial infection.
Patient w/ mononucleosis. Renal and hepatic impairment. Children. Pregnancy and lactation. Monitoring Parameters Periodically monitor renal, hepatic and haematologic function. Monitor for signs of anaphylaxis during 1st dose.
Hypersensitivity to penicillins. History of severe immediate hypersensitivity reaction to another β-lactam agent (e.g. cephalosporins, carbapenem or monobactam), history of cholestatic jaundice/hepatic dysfunction associated w/ amoxicillin and clavulanic acid therapy.
May increase plasma concentration of amoxicillin w/ probenecid. May increase allergic or hypersensitivity reaction w/ concomitant use of allopurinol and amoxicillin. May reduce efficacy of oral oestrogen/progesterone contraceptives.
Symptoms: GI symptoms, fluid and electrolyte imbalances; crystalluria and interstitial nephritis may lead to renal failure. Management: Treat symptomatically w/ attention to water/electrolyte balance. May be removed by haemodialysis.
Intravenous: Store at or below 25°C. Oral: Store at or below 25°C. Reconstituted oral susp: Store between 2-8°C.
Mechanism of Action
Clavulanic acid has a high affinity for and binds to certain β-lactamases that generally inactivate amoxicillin by hydrolysing its β-lactam ring. Combining clavulanate K w/ amoxicillin extends the antibacterial spectrum of amoxicillin to include many bacteria normally resistant to amoxicillin and other penicillins and cephalosporins.