Pantium is a trusted brand of Intas Pharmaceuticals. It contains Pantoprazole, a proton pump inhibitor. It is used for the treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
Parietal (Stomach) cells secrete gastric acid through proton pumps. Pantium inhibits these proton pumps thereby reducing the secretion of acid in the stomach.
Pantium is a prodrug and gets activated by acid present in stomach. Pantoprazole is the most acid stable drug of it’s class.
Pantium is manufactured by Intas Pharmaceuticals Limited, an Indian company headquartered in Ahmedabad, India. Intas is one of the leading multinational pharmaceutical formulation development, manufacturing and marketing companies in the world. Today, Intas is present in more than 85 countries worldwide.
Your doctor may have prescribed Pantium because you could be suffering from Stomach Ulcers, Oesophageal Problems and other acidity related disorders.
Pantium is an orally available medication that contains the active substance Pantoprazole. It works by reducing the amount of acid the stomach produces which helps heal any acid damage to the stomach and oesophagus.
Stomach ulcers are sores on the lining of the stomach and small intestine. This occurs when the protective mucus lining of the stomach becomes ineffective. If the mucus layer is worn away and stops functioning efficiently, the acid can damage the stomach tissue, causing an ulcer. Likewise, whenever the sphincter muscle at the lower end of the oesophagus relaxes at irregular time, allowing stomach acid to rush into the oesophagus which can cause heartburn and other signs.
Patients suffering from acidity related disorders like GERDs and stomach ulcers need to reduce the acid production in order to curb the damage to the stomach and oesophagus. Pantoprazole can be used to treat acidity-related disorders and symptoms that may include:
Gastroesophageal Reflux disease
Helicobacter pylori infection
Difficulty in swallowing
Pantium has been proven to work well among patients with stomach ulcer and oesophagus problems.
As directed by your Physician.
As directed by your Physician.
Adverse Reactions/ Side Effects
Increased risk of Clostridium difficile-associated diarrhoea (CDAD). Headache, dizziness, nausea, vomiting, abdominal pain, flatulence, diarrhoea, constipation, dyspepsia, arthralgia, insomnia, rhinitis, inj site reaction (e.g. thrombophlebitis and abscess). Long-term treatment may lead to atrophic gastritis, symptomatic and asymptomatic hypomagnesaemia, cyanocobalamin malabsorption, and increased risk of osteoporosis-related fracture.
Potentially Fatal: Stevens-Johnson syndrome, toxic epidermal necrolysis and anaphylaxis.
Warnings and Precautions
Gastric malignancy should be ruled out. Consider Zn++ supplementation during IV therapy in patients who are prone to Zn++ deficiency. Pregnancy. Monitoring Parameters Monitor Mg levels prior to initiation and periodically during prolonged use.
Concomitant use w/ rilpivirine, atazanavir and nelfinavir. Lactation.
Increased risk of digoxin-induced cardiotoxic effects. Increased risk of hypomagnesaemia w/ diuretics. May increase INR and prothrombin time of warfarin. May increase serum concentration of methotrexate and saquinavir. Delayed absorption and decreased bioavailability w/ sucralfate. Decreased absorption of ketoconazole, itraconazole.
Potentially Fatal: May decrease serum levels and pharmacological effects of rilpivirine, atazanavir and nelfinavir.
Intravenous: Store between 20-25°C. Oral: Store between 20-25°C