Low initial Cyanocobalamin (Polybion-LC) doses combined with potassium supplementation (as needed) may prevent a hypokalemia seen in patients with severe deficiency.
Patients with pernicious anemia are unusually subject to gastric polyps and have approximately twice the normal incidence of stomach cancer. Because of this, some experts recommend frequent stool guaiac examinations and further diagnostic studies when indicated.
In patients suspected of Cyanocobalamin (Polybion-LC) sensitivity an intradermal test dose of parenteral Cyanocobalamin (Polybion-LC) should be performed prior to initiating therapy with Cyanocobalamin (Polybion-LC) nasal spray or gel.