T BACT

Dosage : Ointment
Contains : Mupirocin
Category : Topical antibiotic
Uses : Primary and secondary skin infections
Price :

Mupirocin is a topical antibacterial agent used for primary and secondary bacterial infections of skin.  It inhibits bacterial action by arresting the bacterial protein synthesis.

 

T Bact is indicated in the following skin conditions:

 

  • Primary Skin Infections:
  • Impetigo
  • Folliculitis
  • Furunculosis
  • Ecthyma

 

Secondary Infections

 

  • Infected dermatosis e.g., infected eczema.
  • Infected traumatic lesions e.g. abrasions, insect bites, minor wounds and burns.

 

Prophylaxis: T-Bach ointment can be used to avoid bacterial contamination of small wounds, incisions and other clean lesions, and to prevent infection of abrasions and small cuts and wounds.

 

Mupirocin is a brand from GlaxoSmithkline which is the world’s leading research based pharmaceutical, healthcare and Vaccine Company. Through its accomplished and dedicated workforce, GSK applies its expertise to innovate various medicines that contributes to the health and well-being of the people of all generations around the world. The company is committed to improve the quality of human life by enabling people to do more, feel better and live longer.

Bacterial skin infections

 

Bacterial skin infections often begin as small, red bumps that slowly increase in size. Some bacterial infections are mild and easily treated with topical antibiotics, but other infections require an oral antibiotic. Different types of bacterial skin infections include:

 

  • Cellulitis
  • Impetigo
  • Boils
  • Leprosy

 

Impetigo is a common and contagious skin infection. Bacteria like Staphylococcus aureus or Streptococcus pyogenes infect the outer layers of skin, called the epidermis. The face, arms, and legs are most often affected.

 

Anyone can get impetigo, but it most commonly affects children, especially those ages 2 to 5.

 

The infection often begins in minor cuts, insect bites, or a rash such as eczema — any place where the skin is broken. But it can also occur on healthy skin.

 

It’s called primary impetigo when it infects healthy skin and secondary impetigo when it occurs in broken skin. It isn’t always easy or necessary to make this distinction.

Dosage

As directed by your Physician.

Administration

As directed by your Physician.

Adverse Reactions/ Side Effects

Significant: Fungal or bacterial superinfection, cutaneous sensitisation reaction or severe local irritation, systemic allergic reactions (e.g. angioedema, urticaria, generalised rash). Eye disorders: Burning and tearing of eyes (nasal ointment). Gastrointestinal disorders: Nausea, dry mouth (nasal ointment).

 

General disorders and administration site conditions: Application site reactions (e.g. localised burning, stinging or tingling sensation, localised pain and swelling), irritation, soreness. Nervous system disorders: Headache, dysgeusia (nasal ointment). Respiratory, thoracic and mediastinal disorders: Rhinitis, sinusitis, respiratory congestion, pharyngitis, cough, post nasal drip, nasal mucosa reactions. Skin and subcutaneous tissue disorders: Pruritus, erythema, skin dryness, rash, contact dermatitis.

Warnings and Precautions

Patient with extensive burns or open wounds. Not indicated for treatment of pressure sores. Renal impairment. Children and elderly. Pregnancy and lactation. Patient Counselling Avoid contact with eyes and mucous membranes.

Contraindications

Hypersensitivity.

Drug Interactions

–

Overdosage

–

Storage

Nasal: Store below 25°C. Do not refrigerate or freeze. Topical/Cutaneous: Store below 25°C. Do not refrigerate or freeze.

Mechanism of Action

Mupirocin, an antibiotic produced by fermentation of Pseudomonas fluorescens, inhibits bacterial protein synthesis by reversibly and specifically binding to bacterial isoleucyl transfer-ribonucleic acid (tRNA) synthetase. It has bacteriostatic effects at minimum inhibitory concentrations and bactericidal effects at higher concentrations.

References

https://india-pharma.gsk.com/media/823459/t-bact-ointment.pdf

https://www.healthline.com/health/impetigo#causes

https://www.mims.com/india/drug/info/mupirocin/?type=full&mtype=generic#Indications

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