Vitamin D deficiency and CVD

AMI  risk is  COMPOUNDED by vitamin D deficiency

  • Vitamin D deficiency  is involved in the development of atherosclerosis and coronary heart disease

  • Low levels of 25(OH)D are associated with higher risk of myocardial infarction in a graded manner, even after controlling for factors known to be associated with coronary artery disease.

GiovannucciE  et al. Arch Int Med 2008; 168 (11): 1174-1180

 

Vitamin D + Atorvastatin FDC

Enhanced effectiveness of  Atorvastatin with optimum Vitamin D3 level

Castrillon JP, et al. International Journal of Endocrinology 2010

 

Indians: A unique population with vitamin D deficiency

70% of Indians today do have vitamin D deficiency

The higher risk of diabetes in Indians as compared to Caucasians  is partly explained by the facts such as

  • persistent micronutrient abnormalities(YajnikCS,et al)

for the same BMI, Asians have a higher body fat percentage and  more central fat, a prominent abdominal obesity, a higher intramyocellular lipid and/or a higher liver fat content compared to Caucasians.( YajnikCS,et al; WulanSN,et al; McCarty MF.)

 

  • have very poor vitamin D status, resulting in up-regulation of parathyroid hormone (PTH) resulting in the high risk for insulin resistance and associated pathologies

 

Benefits of vitamin D supplementation with statins

Vitamin D Supplement helps in

  • Augmentation of CVD risk lowering by statin + Vitamin D
  • Lowered risk of progression of atherosclerosis and CVD

 

Vitamin D Supplement Brands in India

Most of the recommended brands by the doctor:

 

More known brands:

CALCIROL CADILA PHARMA
UPRISE-D3 ALKEM
D-RISE U S V
DEPURA SANOFI
D3 MUST MANKIND
LUMIA SUN
ULTRA-D3 MEYER ORGANICS
DV ALKEM
ARACHITOL NANO ABBOTT
ARACHITOL ABBOTT
TAYO 60 ERIS LIFESCIENCES
VITANOVA D3 EMCURE
CALSHINE P ERIS LIFESCIENCES
KIDRICH-D3 DR REDDYS LABS
MASHYNE U S V
BON-DK GLENMARK PHARMA
D3 HD CORONA REMEDIES
CALDIKIND MANKIND
DEKSEL PULSE PHARMA
D-WELL SUN
D-SOL CIPLA
VITOMIN-D3 CIPLA
DHUP ALBERT DAVID
DVION MERCK LIMITED
D-360 TORRENT PHARMA