| Dosage | : | Gel and Roll on |
| Contains | : | Diclofenac + Linseed oil + Methylsalicylate + Menthol |
| Category | : | Pain management |
| Uses | : | Muscle spasms, swelling and low back pain, Sciatica and other Muscoskeletal painful conditions. |
| Price | : |
Vovilep is a pain relieving gel and roll on, very effective for musculoskeletal painful conditions. It contains Diclofenac which in its topical form is clinically proven to be potent in acute and chronic musculoskeletal pain. Diclofenac acts as a potent analgesic which relieves pain and inflammation. Vovilep also contains Methylsalicylate which is used for temporary relief of muscle or joint pain caused by strains, sprains, arthritis, bruising or backaches. While Methylsalicylate diverts pain sensations experienced by patients, Menthol in Vovilep provides a soothing and cooling action. Linseed oil added to Vovilep gel acts as a local anaesthetic, reducing inflammation while enhancing the absorption of Diclofenac.
Vovilep is manufactured by Pax Healthcare, one of the largest privately held pharmaceutical companies in India, headquartered at Chandigarh, India. The company is WHO & GMP certified pharma franchise over the last one decade, developing, manufacturing and distributing pharmaceutical products in India. Focused on innovation and research, Pax Healthcare is present in more than forty-five therapeutic areas spread across twelve specialties including cardiovascular, gastrointestinal, analgesics, haematinics, anti-infectives, antibiotics, respiratory agents, anti-diabetics and immunological medication.
Your doctor has recommended Vovilep gel as you may be suffering from Muscle pain, Lower back pain or pain due to Sciatica.
Low back pain is due to conditions affecting the spinal cord and nerves, ligaments around the spine and discs, discs between the vertebrae, muscles of the low back, internal organs of the pelvis and abdomen and the skin covering the lumbar area. It can also be caused due to narrowing of the space around the spinal cord which can put pressure on the spinal nerves. Fibromyalgia (widespread muscle aches and tenderness) too causes low back pain.
Massage may relieve chronic low back pain in combination with exercise and stretching. For severe pain or chronic pain, doctors may prescribe medication or injections to the back together with physiotherapy.
Sciatica refers to pain along the sciatic nerve, which branches from the lower back through the hips and buttocks and down each leg. Sciatica pain usually affects only one side of your body.
Sciatica is caused due to a bone spur on the spine, herniated disk or when the narrowing of the spine compresses part of the nerve. This causes inflammation, pain and often numbness in the affected leg. Most sciatica cases are resolved with non-operative treatments in a few weeks. People who have severe sciatica that’s associated with significant leg weakness or bowel or bladder changes may be recommended surgery.
Muscle cramp or muscle spasm is an involuntary contraction of a muscle. Muscle spasms occur suddenly, usually resolve quickly, and are often painful. Muscle cramps happen due to muscle fatigue, dehydration and depletion of electrolytes. It also occurs if the muscle has been previously injured or strained, overstretched or if it has been held in the same position for a prolonged period of time. The muscle cell may run out of energy and fluid leading to a forceful contraction. Muscle spasms occur suddenly, are usually short-lived and often painful.
The initial treatment is to gently stretch the muscle and resolve the acute situation. For treating muscles that have been damaged or strained, medications may be required for pain relief like anti-inflammatories, narcotics and muscle relaxants.
Dosage
As directed by your Physician
Administration
As directed by your Physician
Adverse Reactions/ Side Effects
Diclofenac diethylammonium:
Chest pain & HTN; headache, migraine & hypokinesia; acne, hyperesthesia, photosensitivity reaction, vesiculobullous rash, dry skin, skin carcinoma, application site reaction, contact dermatitis, edema, exfoliation, paresthesia, pruritus, rash & skin ulcer; increased creatinine phosphokinase, AST, ALT & creatinine; hypercholesteremia, hyperglycemia; abdominal pain, diarrhea & dyspepsia; arthralgia, arthrosis, back pain & myalgia; sinusitis, asthma, pneumonia, dyspnea, pharyngitis & rhinitis; allergic reaction, asthenia, neck & eye pain, flu syndrome, infection & conjunctivitis.
As methyl salicylate, The most common adverse effects of therapeutic doses of methyl salicylate are gastrointestinal disturbances such as nausea, dyspepsia, and vomiting. Gastrointestinal symptoms may be minimised by giving methyl salicylate with food. Irritation of the gastric mucosa with erosion, ulceration, haematemesis, and melaena may occur. Histamine H2-antagonists, proton pump inhibitors, and prostaglandin analogues such as misoprostol may be used in the management of methyl salicylate-induced mucosal damage. Slight blood loss, which is often asymptomatic, may occur in about 70% of patients; it is not usually of clinical significance but may, in a few patients, cause iron-deficiency anaemia during long-term therapy. Such occult blood loss is not affected by giving methyl salicylate with food but may be reduced by use of enteric-coated or other modified-release tablets, H2-antagonists, or high doses of antacids. Major upper gastrointestinal bleeding occurs rarely.
Some persons, especially those with asthma, chronic urticaria, or chronic rhinitis, exhibit notable hypersensitivity to methyl salicylate, which may provoke reactions including urticaria and other skin eruptions, angioedema, rhinitis, and severe, even fatal, paroxysmal bronchospasm and dyspnoea. Persons sensitive to methyl salicylate often exhibit cross-sensitivity to other NSAIDs.
Methyl salicylate increases bleeding time, decreases platelet adhesiveness, and, in large doses, can cause hypoprothrombinaemia. It may cause other blood disorders, including thrombocytopenia.
Methyl salicylate and other salicylates may cause hepatotoxicity, particularly in patients with juvenile idiopathic arthritis or other connective tissue disorders. In children the use of methyl salicylate has been implicated in some cases of Reye’s syndrome, leading to severe restrictions on the indications for methyl salicylate therapy in children. For further details see under Reye’s Syndrome.
Methyl salicylate given rectally may cause local irritation; anorectal stenosis has been reported.
Warnings and Precautions
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Contraindications
Diclofenac diethylammonium
Patients with or without chronic asthma in whom attacks of asthma, urticaria or acute rhinitis are precipitated by methyl salicylate or other non-steroidal anti-inflammatory agents (NSAIDs).
- Hypersensitivity to the active substance or any of the excipients,
- Hypersensitivity to propylene glycol, isopropanol or other components of the gel base.
Methyl salicylate
All NSAIDs are contra-indicated in patients with active peptic ulceration; in addition, the non-selective NSAIDs should be used with caution, if at all, in patients with a history of such disorders. To reduce the risk of gastrointestinal effects, NSAIDs may be taken with or after food or milk
Drug Interactions
Diclofenac diethylammonium
Systemic absorption of this medicine is low and hence the risk of an interaction is small. There are no known interactions with this medicine but for a list of interactions known with oral diclofenac the data sheet for oral dosage forms should be consulted.
Overdosage
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Storage
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Mechanism of Action
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References
https://www.medicinenet.com/low_back_pain/article.htm
https://www.webmd.com/back-pain/ss/slideshow-low-back-pain
https://www.medicinenet.com/muscle_spasms/article.htm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847223/
https://www.mayoclinic.org/diseases-conditions/sciatica/symptoms-causes
https://www.ndrugs.com/?s=vovilep